Established in 2006, the Airport Health Organisation (APHO), Cochin serves as the designated public health authority at Cochin International Airport overseeing the implementation of public health measures for international travellers in accordance with national and international health regulations.

To strengthen preparedness for public health emergencies at Cochin Airport, the existing Quarantine centre was upgraded to a modern state-of-the-art Quarantine-cum-Isolation Centre in 2025 for the safe isolation and management of suspected international travellers while ensuring uninterrupted routine airport health operations. The organisation is further equipped with a dedicated vector surveillance laboratory, along with facilities for training, conferences, and capacity-building activities.

APHO Cochin is also an authorized Yellow Fever Vaccination Centre.

Additionally, APHO Cochin oversees and coordinates the public health activities at Kannur International Airport.