The Necessary Information For Yellow Fever Vaccine Beneficiaries

• All vaccine beneficiaries have to wait for 30 minutes after receiving the vaccination and
• Inform immediately to the doctor on duty in case of any uneasiness, side effects, rashes , reaction or any other adverse event.

Who should not get yellow fever vaccine?

• Anyone with allergy to eggs, chicken proteins, or gelatin,
• who had a severe allergic reaction to a previous dose of Yellow fever vaccine (Tell your doctor if you have any severe allergies)
• You are pregnant, or could be pregnant now or in the next two weeks
• Children younger than 09 months of age,
• HIV/AIDS patient.
• Immune system is weakened as a result of cancer or other medical conditions, a transplant, or radiation or drug treatment (such as steroids or cortisone, cancer chemotherapy, or other drugs that affect immune cell function).
• Persons with acute/moderate illness (with or without a fever) should postpone receiving this vaccine until they are well.
• Patients with thymus disorder, such as myasthenia gravis, DiGeorge syndrome, or thymoma or Thymus removed.
• Patients with major liver or kidney disease

Please note :

• Nursing mothers should avoid or postpone travel to an area where there is risk of yellow fever.
• Adults 60 years of age and older might be at increased risk for severe problems following vaccination.

Mild Side Effects of Vaccination

• Yellow fever vaccine has been associated with fever and with aches, soreness, redness or swelling where the shot was given. These problems occur in up to 1 out of 4 persons. They usually begin soon after the shot, and can last up to a week.
• Most people may have a slight sore arm.
• 2-10% may feel tired, headache, muscle aches, fever for 24 hours starting 3-9 days after the vaccine
• 1% need to curtail regular activities

More Serious Side Effects of Vaccination

• The risk of a vaccine causing serious harm, or death, is extremely low.
• Severe allergic reaction to a vaccine component (about 1 person in 55,000).
• Severe nervous system reaction (about 1 person in 125,000).
• Life-threatening severe illness with organ failure (about 1 person in 250,000). More than half the people who suffer this side effect die. The last two complications have never been reported with a booster dose.
• 1 in 130,000 will get immediate hypersensitivity – rash, itching faint or asthma – this is why you need to wait 30 minutes in the clinic
• 0.09-2.5 per million will get inflammation of multiple organs e.g. lungs, kidney, liver, spleen, skin, blood stream
• 1 in 8 million will get encephalitis (inflammation of the brain)

What if there is a severe reaction? What should we look for?

• Look for any unusual condition, such as a high fever, behavior changes, or flu-like symptoms
• Signs of an allergic reaction can include difficulty in breathing, hoarseness or wheezing, hives, paleness, weakness, a fast heart¬beat, or dizziness within a few minutes to a few hours after the shot.

What should we do?

• Call a doctor, or get the person to a doctor right away.
• Tell the doctor what happened, the date and time it happened, and when the vaccination was given.
• Keep informed the APHO, about any adverse reaction and treatment/hospital details.

NOTE:- Exemption or contraindication to yellow fever Vaccination does not provide any immunity from quarantine (isolation)
Yellow fever Certificate- Only WHO recommended yellow fever card is to be used.
Note-

1. This certificate is valid only if the vaccine or prophylaxis has been approved by the World Health Organization.
2. This certificate must be signed in hand of the clinician who shall be a medical practitioner or other authorised health worker, supervising the administration of vaccine or prophylaxis. The certificate must also bear the official stamp of administering centre; however, this shall not be an accepted substitute for the signature.
3. Any amendment of this certificate, or erasure, or failure to complete any part of it, may render it invalid.
4. The validity of this certificate is life of person vaccinated i.e. for whole life. The certificate shall be fully completed in English or in French. The certificate may also be completed in another language on the same document, in addition to either English or French.

Passengers planning to travel to or passing through any of the Yellow Fever endemic country even while seated within the aircraft, are required to have the vaccination and in possession of VALID YELLOW FEVER CERTIFICATE in Original at all times, complete in all respects as per standards laid down by the WHO in its Regulations.

Since the Vaccine is developed and prepared in Chick Embryo, anyone having Allergy to Egg protein must not take the vaccination, as it is likely to lead to severe anaphylactic reaction, which could be fatal. Besides this other absolute contradictions are deficient immunity in individuals under medication for Thymus disease, Cancer, HIV/AIDS, on Corticosteroids for any reasons, suffering from any severe allergies. Those suffering from severe Asthmatic conditions should also avoid taking this vaccination.

The vaccination is valid after 10 days from the date of vaccination and duration of its validity is the life of the person vaccinated.

Vaccination Procedure

The vaccine beneficiary moves in following direction Registration counter → waiting area → Injection Room → Observation Room

• Yellow Fever Vaccination received in India is valid only if it is received from Govt. of India recognized centers only.
• 10 PERSONS ARE REQUIRED IN A BATCH (As the vaccine available vial is of 10 dose each & it is opened only when 10 persons are available)
• FEE - RS.300/- FOR ONE VACCINE, fixed by Govt. of India from time to time.

Mandatory Requirement – Original Passport

• There has to be gap of four weeks between two different live vaccines.

Please Note:

• The vaccination services are to be provided as first come first served basis.
• The registration / token distribution system may be followed to maintain the first come first serve system.
• At time of registration, the Travel Document (passport) is to be checked and all the vaccinees are instructed to read the necessary information regarding Yellow Fever Vaccination displayed in the registration / waiting area.
• The vaccinees are informed to bring/keep the Travel Document (passport) and the vaccination fee Rs.300/- with them at the vaccination time.
• All the vaccinees are instructed to wait in the waiting area and the vaccinees are called for vaccination in batches of 10 persons in vaccination room.
• All the vaccinees are informed and allowed to read about the side effects / adverse reactions and other related information about Yellow Fever Vaccination.
• The informed consent is to be taken from all the vaccinees.
• The entries are filled up in the vaccination register from Travel Document (passport) & subsequently the fee for the vaccination is collected and the receipt for the same is given to vaccinee.
• The vaccinees are directed to complete the entries related to vaccine in WHO Yellow Fever Vaccination card and directed for vaccine inoculation.
The doctor/nurse starts the vaccination procedure as follows:
1. Checks the Vial Viability Marker.
2. The required amount of diluents mixed in the vial with 5ml disposable plastic syringe.
3. All the bio-medical waste are segregated and collected/disposed in the respective bags at the time of procedure only as per biomedical waste rules.
4. The water swab is used to clean the inoculation area.
5. The vaccination dose i.e. 0.5ml for everybody is inoculated to the vaccinee with 1ml disposable/AD plastic syringe.
6. After inoculation the vaccinees are asked to wait for 30 minutes and inform about any side effects / adverse reactions to doctor on duty.

Yellow Fever Vaccine is an attenuated, live-virus preparation of the 17D strain of yellow fever virus grown in leucosis-free chick embryos. A single dose correctly given confers immunity in 100% of recipients. Protective immunity is achieved only after 10 days of yellow fever vaccination and persists till life of person vaccinated. This vaccine is given as a single injection given subcutaneously. Yellow fever Vaccination Certificate becomes valid only after 10 days of vaccination.

Type of vaccine	Live viral
Number of doses	One dose of 0.5 ml subcutaneously
Route of Administration	Sub-cutaneous
Contraindications	Egg allergy; immune deficiency from medication or disease; symptomatic HIV infection; hypersensitivity to previous dose; pregnancy
Adverse reactions	Hypersensitivity to egg; rarely, encephalitis in the very young; hepatic failure. Rare reports of death from massive organ failure.
Special precautions	Do not give before six months of age; avoid during pregnancy
Storage temperature	+2 to +8 degrees centigrade

Yellow Fever Endemic Countries – the list is updated on 03 January 2023 by WHO

Africa			Central and South America
Angola Benin Burkina Faso Burundi Cameroon Central African Republic Chad Congo Cote d’Ivoire Democratic Republic of Congo Equatorial Guinea	Ethiopia Gabon The Gambia Ghana Guinea Guinea-Bissau Kenya Liberia Mali Mauritania Niger Nigeria	Senegal Sierra Leone Sudan South Sudan Togo Uganda	Argentina Bolivia Brazil Colombia Ecuador French Guiana Guyana Panama Paraguay Peru Suriname Trinidad and Tobago Venezuela

Requirement of Yellow Fever Vaccine Boster Dose for passengers travelling from/to Non-Endemic Countries- regarding

Unauthorized Vaccination Centres

Model Consent Form for YFVC Centres

YFVC order dated 13.02.2024

YFVC order dated 28.07.2023

YFVC order dated 29.03.2023

YFVC order dated 12.12.2008